What are senescent cells and how can we identify them?

Cellular senescence serves as a protective mechanism in our body against the development of cancer cells. However, before a healthy cell enters this state of dormancy, it undergoes a stressful process: step by step, central cell organelles, particularly the mitochondria, lose their function. As a result, acids and free radicals accumulate in the cell, making its normal metabolic and life functions increasingly impossible.

The cell now has the choice between becoming a single-celled organism in the form of a cancer cell or entering operational shutdown. Similar to a coffee machine that is forced to stop when it becomes increasingly calcified until it is repaired, the cell also has a system that ensures operational shutdown to prevent greater damage. This shutdown of cell function is better than allowing a cancer cell to develop. The gene responsible for this cell shutdown is the so-called tumor suppressor gene p53. Without this gene, we would suffer from cancer in 100 percent of cases.

During shutdown (senescence), the cell has the opportunity to repair damaged cell organelles. P53 also plays a central role here: it protects the cell, supports repair processes, and can later specifically guide senescent cells into programmed cell death if recovery is not possible. Secondary plant compounds contribute significantly to promoting these protective and repair mechanisms.

GYCELL was developed as a senolytic for this type of cell for your protection and provides a unique combination of secondary plant compounds for this purpose.

Dr. Kay Bredehorst

(Founder and developer of Cell Education - a training platform for cell therapy with over 40,000 doctors)